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We are so sad to report the passing of Afeni Shakur, the mother of the late 2Pac. In addition to giving birth to one of the best rappers of all time, Afeni was a respected activist and former member of the Black Panther Party.

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The mother of late rapper Tupac, died Monday night, People Magazine reports. She was at 69-years-old.

The Main County Sherrif’s office reportedly responded to an emergency report of a possible cardiac arrest at Davis’ Sausalto, California home at 9:30pm Monday night.

She was transferred to the hospital where she died at 10:28 pm. The coroners office will be investigating the exact cause of her death, the Sheriff’s office said.

The former Black Panther activist was the subject of one of Tupac’s most memorable hits, “Dear Mama.”

Our heart go out to the family and friends during this time of grief.

Take a look at Afeni talking about what she misses about her son in the video above from 2011. And enjoy 2Pac’s classic dedication to her.